THE 2-MINUTE RULE FOR IONOMYCIN CALCIUM

The C-C motif chemokine receptor 8 (CCR8) is a class A G-protein coupled receptor which has emerged as being a promising therapeutic focus on in cancer. Targeting CCR8 by having an antibody has gave the impression to be an attractive therapeutic solution, but the molecular basis for chemokine-mediated activation and antibody-mediated inhibition of